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The high prevalence of chronic pain in the United States continues to require discussion about what are really the most effective ways to help individuals with chronic pain while, at the same time, limiting the risks for complications commonly seen with the use of pain medications, particularly opioid analgesics.

These medications have dominated the chronic pain discourse over recent years, not because of their effectiveness, but because of their potential side effects and risks of misuse and abuse, including overdose and death.

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