(Bloomberg) – The death toll from earthquakes that struck southern Japan rose to 42 and the economic impact began to reverberate Monday as companies surveyed damage and the potential effects on production from supply-chain disruptions.

The quakes that struck the island of Kyushu since Thursday evening included some of the nation's most devastating earthquakes since March 2011. There are 201 people seriously injured, 838 have light injuries, and 110,816 have been evacuated to shelters, according to Kumamoto Prefecture's disaster countermeasures office. There has been additional damage in neighboring prefectures including Oita.

The Topix index slumped 3% to 1,320.15 at the close in Tokyo, with all but one of its 33 industry groups falling, after rising last week by the most in two months. The Nikkei 225 Stock Average dropped 3.4% to 16,275.95.

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